Communication Dans Un Congrès Année : 2017

High throughput three-dimensional imaging of myelin fibers in the whole mouse brain

Carole Frindel
David Rousseau
  • Fonction : Auteur
  • PersonId : 919340
Max Langer
Tae-Hee Cho

Résumé

Injury to the white matter (WM) leads to severe functional loss in many neurological diseases such as stroke and multiple sclerosis. In-vivo neuroimaging techniques such as diffusion tensor imaging are becoming important tools for the diagnosis of WM abnormalities. However, these tools still present limitations and there is a crucial need for whole-brain ex-vivo complementary approaches to overcome them [1]. We propose a novel three dimensional (3D) imaging method to map the myelin fibers in the whole mouse brain with high throughput using in-line phase contrast X-ray tomography.
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Dates et versions

hal-01598092 , version 1 (23-01-2025)

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  • HAL Id : hal-01598092 , version 1

Citer

Hugo Rositi, Violaine Hubert, Loriane Weber, Elodie Ong, Lise-Prune Berner, et al.. High throughput three-dimensional imaging of myelin fibers in the whole mouse brain. TOPIM Neuroimaging - from Molecules to networks, Feb 2017, Les Houches, France. ⟨hal-01598092⟩
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